Cardiac-specific deficiency of the mitochondrial calcium uniporter augments fatty acid oxidation and functional reserve

2019
Written By Stellate Comms

Altamimi TR, Karwi QG, Uddin GM, Fukushima A, Kwong JQ, Molkentin JD, Lopaschuk GD (2019) Journal of Molecular and Cellular Cardiology

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Systems analysis of the 22q11.2 microdeletion syndrome converges on a mitochondrial interactome necessary for synapse function and behavior
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The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle