Systems analysis of the 22q11.2 microdeletion syndrome converges on a mitochondrial interactome necessary for synapse function and behavior

2019
Written by Stellate Comms

Gokhale A, Hartwig C, Freeman AAH, Bassell JL, Zlatic SA, Sapp Savas C, Vadlamudi T, Abudulai F, Pham TT, Crocker A, Werner E, Wen Z, Repetto GM, Gogos JA, Claypool SM, Forsyth JK, Bearden CE, Glausier J, Lewis DA, Seyfried NT, Kwong JQ, Faundez V (2019) Journal of Neuroscience

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Mitochondrial dysfunction and oxidative stress in heart disease
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Cardiac-specific deficiency of the mitochondrial calcium uniporter augments fatty acid oxidation and functional reserve